Common variable immune deficiency: respiratory manifestations, pulmonary function and high-resolution CT scan findings

Pulmonary manifestations of immune deficiency diseases.

The defense of the respiratory system against infection involves a complex interplay of the humoral immune system and the cellular immune system with complement and phagocytic cells. The respiratory tract is an important portal of entry for infection, and it is therefore not surprising that many immune deficiencies present initially with a respiratory infection. Thus, pediatric pulmonologists m...

Idiopathic pulmonary fibrosis: spectrum of high-resolution CT findings.

OBJECTIVE Characteristic high-resolution CT (HRCT) findings of idiopathic pulmonary fibrosis (IPF) include reticulation, architectural distortion, and honeycombing involving mainly the lung periphery and the lower lobes. In 50% of IPF patients, HRCT is nonspecific. This article illustrates the HRCT findings of IPF correlating with the pathology. CONCLUSION The spectrum of HRCT manifestations ...

High-Resolution CT Findings of Re-Expansion Pulmonary Edema

OBJECTIVE To describe the high-resolution CT (HRCT) findings of re-expansion pulmonary edema (REPE) following a thoracentesis for a spontaneous pneumothorax. MATERIALS AND METHODS HRCT scans from 43 patients who developed REPE immediately after a thoracentesis for treatment of pneumothorax were retrospectively analyzed. The study group consisted of 41 men and two women with a mean age of 34 y...

Fundamentals of High-Resolution Lung CT: Common Findings, Common Patterns, Common Diseases, and Differential Diagnosis

High-resolution computed tomography and pulmonary function in children with common variable immunodeficiency.

High-resolution computed tomography (HRCT) may be useful to monitor lung disease in children with common variable immunodeficiency disorder (CVID). We evaluated interobserver agreement and correlation with pulmonary function tests (PFTs) for automated quantification and visual scoring of air trapping and airway wall thickening on HRCT in paediatric CVID patients. In a cohort of 51 children with...